Glioblastomas located in proximity to the subventricular zone (SVZ) exhibited enrichment of gene expression profiles associated with the cancer stem cell state.
Tyler C SteedJeffrey M TreiberBirra TahaH Billur EnginHannah CarterKunal S PatelAnders M DaleBob S CarterClark C ChenPublished in: Journal of neuro-oncology (2020)
An unbiased analysis of TCIA suggests that glioblastomas located in proximity to the SVZ exhibited mRNA expression profiles associated with stem cell properties, increased DNA repair capacity, and is associated with poor clinical survival.