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Mapping the m1A, m5C, m6A and m7G methylation atlas in zebrafish brain under hypoxic conditions by MeRIP-seq.

Wei LiXiaoyu LiXunjie MaWei XiaoJing-Jing Zhang
Published in: BMC genomics (2022)
Our study presents the first comprehensive atlas of m1A, m5C, m6A and m7G in the epitranscriptome of the zebrafish brain and reveals the distribution of these modifications in mRNA under hypoxic conditions. These data provide an invaluable resource for further research on the involvement of m1A, m5C, m6A and m7G in the regulation of miRNA and repeat elements in vertebrates, and provide new thoughts to study the brain hypoxic injury on the aspect of epitranscriptome.
Keyphrases
  • resting state
  • white matter
  • single cell
  • genome wide
  • functional connectivity
  • dna methylation
  • gene expression
  • electronic health record
  • rna seq
  • big data
  • brain injury
  • blood brain barrier