Phosphorylation of Microglial IRF5 and IRF4 by IRAK4 Regulates Inflammatory Responses to Ischemia.

Conelius NgwaAbdullah Al MamunYan XuRomana SharmeenFudong Liu

Published in: Cells (2021)

IRAK4 signaling is critical for microglial inflammatory responses and a potential therapeutic target for neuroinflammatory diseases including cerebral ischemia.

Keyphrases

cerebral ischemia
subarachnoid hemorrhage
inflammatory response
lipopolysaccharide induced
lps induced
dendritic cells
blood brain barrier
brain injury
neuropathic pain
spinal cord injury
human health
immune response
risk assessment
climate change