Telomere Shortening in Middle-Aged Men with Sleep-disordered Breathing.

Laurent BoyerEtienne AudureauLaurent MargaritElisabeth MarcosEmilie BizardPhilippe Le CorvoisierIsabelle Macquin-MavierGeneviève DerumeauxThibaud DamyXavier DrouotAla Covali-NorocJorge BoczkowskiSylvie Bastuji-GarinSerge Adnot

Published in: Annals of the American Thoracic Society (2018)

Intermittent hypoxemia due to obstructive sleep apnea syndrome is a major contributor to telomere shortening in middle-aged men. Oxidative stress may explain this finding.

Keyphrases

middle aged
obstructive sleep apnea
oxidative stress
positive airway pressure
dna damage
high intensity
ischemia reperfusion injury
case report
diabetic rats
sleep apnea
signaling pathway
heat shock
heat stress