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Targeting myeloid checkpoint Siglec-10 reactivates antitumor immunity and improves anti-programmed cell death 1 efficacy in gastric cancer.

Kunpeng LvMengyao SunHanji FangJieti WangChao LinHao LiuHeng ZhangHe LiHongyong HeYun GuRuochen LiFei ShaoJiejie Xu
Published in: Journal for immunotherapy of cancer (2023)
T cells, ultimately facilitating immune evasion. Targeting Siglec-10 represents a potential strategy for immunotherapy in GC.
Keyphrases
  • cancer therapy
  • dna damage
  • dendritic cells
  • bone marrow
  • acute myeloid leukemia
  • cell cycle
  • risk assessment
  • oxidative stress
  • mass spectrometry