NS3 Resistance-Associated Variants (RAVs) in Patients Infected with HCV Genotype 1a in Spain.

María Ángeles Jimenez-SousaMónica Gutiérrez-RivasAlejandro Álvaro-MecaMónica García-ÁlvarezP Richard HarriganCesare Giovanni FedeleVerónica BrizSonia Vázquez-MorónSalvador Resino

Published in: PloS one (2016)

The prevalence of most resistance-associated variants in NS3 was low in patients infected with HCV GT1a in Spain, except for Q80K (11.1%), which was also notably higher in HIV/HCV-coinfected patients. The vast majority of Q80K polymorphisms were detected in GT1a clade I.

Keyphrases

end stage renal disease
hepatitis c virus
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
gene expression
patient reported outcomes
copy number
dna methylation
hiv aids