Autoantibodies in patients with interleukin 12 receptor beta 1 deficiency.
Vincenzo RoncaQu Bo ChenVasiliky LygouraImen Ben-MustaphaZakera ShumsMehdi TrifaMarco CarboneClara MancusoChiara MilaniFrancesca BernuzziXiong MaNourhen AgrebiGary L NormanChristopher ChangMerrill Eric GershwinMohamed-Ridha BarboucheInvernizzi PietroPublished in: Journal of digestive diseases (2019)
This is the first report of a serological analysis in patients with an IL-12Rβ1 deficiency. Despite the difficulty in interpreting the role of the IL-12, the evidence of liver-specific autoantibodies confirms the importance its signal in liver autoimmunity.