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Game theoretic centrality: a novel approach to prioritize disease candidate genes by combining biological networks with the Shapley value.

Min Woo SunStefano MorettiKelley M PaskovNate T StockhamMaya VarmaBrianna S ChrismanPeter Y WashingtonJae-Yoon JungDennis Paul Wall
Published in: BMC bioinformatics (2020)
Game theoretic centrality can prioritize influential, disease-associated genes within biological networks, and assist in the decoding of polygenic associations to complex disorders like autism.
Keyphrases
  • autism spectrum disorder
  • genome wide
  • virtual reality
  • intellectual disability
  • gene expression