Prediction of therapy response in bone-predominant metastatic breast cancer: comparison of [18F] fluorodeoxyglucose and [18F]-fluoride PET/CT with whole-body MRI with diffusion-weighted imaging.

Gurdip K AzadBenjamin P TaylorAdrian GreenInes SandriAngela SwampillaiMark HarriesHartmut KristeleitJanine MansiVicky GohGary J R Cook

Published in: European journal of nuclear medicine and molecular imaging (2018)

FDG PET/CT and WB-MRI best predicted clinical non-PD and both FDG and NaF PET/CT predicted PFS < 24 weeks. Lesional response heterogeneity occurs with all modalities and flare is common with NaF PET/CT.

Keyphrases

pet ct
diffusion weighted imaging
contrast enhanced
metastatic breast cancer
positron emission tomography
magnetic resonance imaging
computed tomography
magnetic resonance
single cell
bone mineral density
stem cells
bone marrow