Comparative analysis of eleven SARS-CoV-2 immunoassays and neutralisation data: time to enhance standardisation and correlation of protection.

Jorge Julio Cabrera-Alvargonzalez Carlos Davina-Nunez Sonia Rey-Cao Leticia Rodriguez Calviño Sergio Silva-Bea Elena Gonzalez-Alonso Raquel Carballo-FernándezCarmen Lameiro VilariñoSandra Cortizo-VidalPilar Valiño-PrietoMiriam Rodriguez-PerezSonia Pérez-CastroIsabel López MiragayaArturo Fernández-NogueiraVictor Del Campo-Perez Benito Regueiro

Published in: Infectious diseases (London, England) (2024)

High-throughput immunoassays are good predictors of neutralising capacity. Updated targets and better standardisation would be required to find an effective correlate of protection, especially to account for antibodies against new variants.

Keyphrases

sars cov
high throughput
respiratory syndrome coronavirus
electronic health record
copy number
single cell
dna methylation
machine learning
data analysis