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Olfactory cleft mucus inflammatory proteins in CRS: a case-control study.

Timothy L SmithRodney J SchlosserZachary M SolerJess C MaceJose L MattosVijay R RamakrishnanDaniel M BeswickJeremiah A AltJennifer K Mulligan
Published in: International forum of allergy & rhinology (2021)
This study confirmed that OC inflammatory proteins vary both by disease phenotype and in their association with OD. Type 2 inflammatory mediators are increased in CRS, especially within the CRSwNP group. However, a substantial proportion of CRSsNP also express type 2 inflammatory mediators. Further research is necessary to understand the complex roles OC mucous inflammatory proteins might play in defining endotype and in impacting CRS-related OD. ©2021 ARSAAOA, LLC.
Keyphrases
  • oxidative stress