Electrochemical Detection of Dopamine and Riboflavine on a Screen-Printed Carbon Electrode Modified by AuNPs Derived from Rhanterium suaveolens Plant Extract.
Sabrine ChellyMeryam ChellyRayhane ZribiRadhouane GdouraHanen Bouaziz-KetataGiovanni NeriPublished in: ACS omega (2021)
A AuNP-modified screen-printed carbon electrode (AuNP/SPCE) for monitoring important biomolecules, such as dopamine (DA) and riboflavin (RF), having a high potential for personalized medicine and for continuous monitoring of human health is here proposed. AuNPs were synthesized using the extract of Rhanterium suaveolens as a reducing medium and were characterized by UV-vis spectroscopy, dynamic light scattering (DLS), and scanning and transmission electron microscopy (SEM and TEM). The synthesized AuNPs appear spherical and present a bimodal size distribution with a maximum centered at around 30-50 nm. Cyclic voltammetry (CV) experiments demonstrated that the modified AuNP/SPCE sensor exhibits superior electrochemical performances to the bare SPCE. Low limits of detection (LODs) of 0.2 and 0.07 μM at S/N = 3 and sensitivities of 550.4 and 2399 μA mM-1 cm-2 were registered for DA and RF detection, respectively. Results demonstrate the promising electrochemical characteristics of the synthesized AuNPs and developed AuNP/SPCE electrochemical sensor for the determination of these important biomolecules.
Keyphrases
- label free
- human health
- molecularly imprinted
- gold nanoparticles
- electron microscopy
- risk assessment
- ionic liquid
- loop mediated isothermal amplification
- high resolution
- real time pcr
- high throughput
- uric acid
- solid phase extraction
- photodynamic therapy
- solid state
- mass spectrometry
- low cost
- electron transfer
- tandem mass spectrometry
- sensitive detection
- monte carlo
- oxide nanoparticles