What Determines Cognitive Functioning in the Oldest-Old? The EMIF-AD 90+ Study.
Nienke LegdeurMaryam BadissiMaqsood YaqubNina BekerCarole H SudreMara Ten KateMark Forrest GordonGerald NovakFrederik BarkhofBart N M van BerckelHenne HolstegeMajon MullerPhilip ScheltensAndrea Britta MaierPieter Jelle VisserPublished in: The journals of gerontology. Series B, Psychological sciences and social sciences (2021)
In the oldest-old, physical parameters, nutritional status, HbA1c, WMH, hippocampal atrophy, and amyloid binding are associated with cognitive impairment. Physical performance may affect cognition through hippocampal atrophy. This study highlights the importance to consider multiple factors when assessing cognition in the oldest-old.