Development and validation of a sensitive and reliable targeted metabolomics method for the quantification of cardiovascular disease-related biomarkers in plasma using ultrahigh-performance liquid chromatography-tandem mass spectrometry.
Shanshan GaoXiangyi WangJianpeng HuangYing ZhuRuiping ZhangJiuming HeZeper AblizPublished in: Rapid communications in mass spectrometry : RCM (2022)
The targeted metabolomics method was shown to have a powerful ability to accurately analyze metabolic biomarkers, thereby providing valuable information for large-scale biomarker validation and clarifying the potential material basis of cardiovascular disease for clinical diagnosis or early warning.
Keyphrases
- cardiovascular disease
- liquid chromatography tandem mass spectrometry
- mass spectrometry
- simultaneous determination
- cancer therapy
- ms ms
- solid phase extraction
- type diabetes
- cardiovascular events
- cardiovascular risk factors
- liquid chromatography
- metabolic syndrome
- risk assessment
- human health
- tandem mass spectrometry