Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroprevalence: Navigating the absence of a gold standard.

Sahar SaeedSheila F O'BrienKento AbeQi-Long YiBhavisha RathodJenny WangMahya Fazel-ZarandiAshleigh TuiteDavid FismanHeidi WoodKaren ColwillAnne-Claude GingrasSteven J Drews
Published in: PloS one (2021)
Our results confirmed very low seroprevalence after the first wave in Canada. Given the dynamic nature of this pandemic, Bayesian Latent Class Models can be used to correct for imperfect test characteristics and waning IgG antibody signals.