Integration of Antiangiogenic Therapy with Cisplatin and Gemcitabine Chemotherapy in Patients with Nasopharyngeal Carcinoma.
Wan Qin ChongChwee Ming LimArvind Kumar SinhaChee Seng TanGloria Hui Jia ChanYiqing HuangNesaretnam Barr KumarakulasingheRaghav SundarAnand D JeyasekharanWoei Shyang LohJoshua K TayKritika YadavLing-Zhi WangAndrea L WongLi Ren KongRoss Andrew SooJieying Amelia LauYu Yang SoonRobby Miguel GohFrancis Cho Hao HoSiew Meng ChongSoo Chin LeeKwok Seng LohBee Choo TaiBoon Cher GohPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2020)
Bevacizumab 7.5 mg/kg with cisplatin and gemcitabine was well tolerated. Promising tumor response was observed and supported mechanistically by positive effects on tumor perfusion and immune cell trafficking into the tumor.