Genetic variation associated with childhood and adult stature and risk of MYCN-amplified neuroblastoma.

Eleanor C SemmesErica ShenJennifer L CohenChenan ZhangWenjie JiaoJillian H HurstKyle M Walsh

Published in: Cancer medicine (2020)

Genetic propensity to taller childhood height and shorter adult height were associated with MYCN-amplified neuroblastoma risk, suggesting that biological pathways affecting growth trajectories and pubertal timing may contribute to MYCN-amplified neuroblastoma etiology.

Keyphrases

childhood cancer
body mass index

young adults
early life

depressive symptoms
genome wide

gene expression
physical activity