A Systems Biology Workflow for Drug and Vaccine Repurposing: Identifying Small-Molecule BCG Mimics to Reduce or Prevent COVID-19 Mortality.

Published in: Pharmaceutical research (2020)

Our results provide systems biology support for using BCG and small-molecule BCG mimics as putative vaccine and drug candidates against emergent viruses including SARS-CoV-2.

Keyphrases

small molecule
sars cov
protein protein
respiratory syndrome coronavirus
coronavirus disease
cardiovascular events
adverse drug
drug induced
emergency department
coronary artery disease
drug discovery