Chemical Compositions, Mosquito Larvicidal and Antimicrobial Activities of Essential Oils from Five Species of Cinnamomum Growing Wild in North Central Vietnam.
Do N DaiNguyen T ChungLe T HuongNguyen Huy HungDao T M ChauNguyen T YenWilliam N SetzerPublished in: Molecules (Basel, Switzerland) (2020)
Members of the genus Cinnamomum (Lauraceae) have aromatic volatiles in their leaves and bark and some species are commercially important herbs and spices. In this work, the essential oils from five species of Cinnamomum (C. damhaensis, C. longipetiolatum, C. ovatum, C. polyadelphum and C. tonkinense) growing wild in north central Vietnam were obtained by hydrodistillation, analyzed by gas chromatography and screened for antimicrobial and mosquito larvicidal activity. The leaf essential oil of C. tonkinense, rich in β-phellandrene (23.1%) and linalool (32.2%), showed excellent antimicrobial activity (MIC of 32 μg/mL against Enterococcus faecalis and Candida albicans) and larvicidal activity (24 h LC50 of 17.4 μg/mL on Aedes aegypti and 14.1 μg/mL against Culex quinquefasciatus). Cinnamomum polyadelphum leaf essential oil also showed notable antimicrobial activity against Gram-positive bacteria and mosquito larvicidal activity, attributable to relatively high concentrations of neral (11.7%) and geranial (16.6%). Thus, members of the genus Cinnamomum from Vietnam have shown promise as antimicrobial agents and as potential vector control agents for mosquitoes.
Keyphrases
- aedes aegypti
- essential oil
- zika virus
- dengue virus
- candida albicans
- staphylococcus aureus
- gas chromatography
- genetic diversity
- gas chromatography mass spectrometry
- biofilm formation
- tandem mass spectrometry
- high resolution mass spectrometry
- escherichia coli
- risk assessment
- gram negative
- solid phase extraction
- liquid chromatography
- cystic fibrosis
- artificial intelligence