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11,12 and 14,15 epoxyeicosatrienoic acid rescue deteriorated wound healing in ischemia.

Katharina SommerHeike JakobFarsin BadjlanDirk HenrichJohannes FrankIngo MarziAnna Lena Sander
Published in: PloS one (2019)
In summary, EET improve impaired wound healing caused by ischemia as they enhance neovascularization and alter inflammatory response in wounds. Thus elevating lipid mediator level as 11,12 and 14,15 EET in wounds might be a successful strategy for amelioration of deranged wound healing under ischemia.
Keyphrases
  • wound healing
  • inflammatory response
  • lipopolysaccharide induced
  • vascular endothelial growth factor
  • diabetic retinopathy
  • toll like receptor
  • optical coherence tomography