Predictive role of atrial fibrillation in cognitive decline: a systematic review and meta-analysis of 2.8 million individuals.
Yu Han KohLeslie Zhi Wei LewKyle B FrankeAdrian D ElliottDennis H LauAnand ThiyagarajahDominik K LinzMargaret ArstallPhillip J TullyBernhard T BauneDian A MunawarRajiv MahajanPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2022)
Atrial fibrillation is associated with increased risk of cognitive impairment. The association with cerebral small vessel disease and cerebral atrophy secondary to cardioembolism and cerebral hypoperfusion may suggest a plausible link in the absence of clinical stroke. PROSPERO CRD42018109185.
Keyphrases
- atrial fibrillation
- cognitive decline
- cognitive impairment
- subarachnoid hemorrhage
- mild cognitive impairment
- left atrial
- catheter ablation
- oral anticoagulants
- cerebral ischemia
- left atrial appendage
- direct oral anticoagulants
- heart failure
- percutaneous coronary intervention
- cerebral blood flow
- coronary artery disease
- left ventricular
- acute coronary syndrome
- venous thromboembolism