Dementia with lewy bodies: GBA1 mutations are associated with cerebrospinal fluid alpha-synuclein profile.
Stefanie LercheGerrit MachetanzIsabel WursterBenjamin RoebenMilan ZimmermannAndrea PilottoOliver PreischeElke StranskyChristian DeuschleAnn-Kathrin HauserClaudia SchulteIngolf LachmannKatharina WaniekThomas GasserDaniela BergWalter MaetzlerKathrin BrockmannPublished in: Movement disorders : official journal of the Movement Disorder Society (2019)
Similar to PD, pathogenic GBA1 mutations seem to be associated with CSF alpha-synuclein profiles in dementia with Lewy bodies. That might be useful for patient stratification for specific alpha-synuclein-lowering compounds. © 2019 International Parkinson and Movement Disorder Society.