RepCOOL: computational drug repositioning via integrating heterogeneous biological networks.

Ghazale FahimianJavad ZahiriSeyed Shahriar ArabReza H Sajedi

Published in: Journal of translational medicine (2020)

Results show the potency of the proposed method in detecting true drug-disease relationships. RepCOOL suggested four new drugs for breast cancer stage II namely Doxorubicin, Paclitaxel, Trastuzumab, and Tamoxifen.

Keyphrases

drug induced
adverse drug
drug delivery
epidermal growth factor receptor
emergency department
cancer therapy
metastatic breast cancer