IFN-α2 Autoantibody Screening and Functional Evaluation in Viral and Bacterial Infections.

Maaike CockxSophie SteelsBirthe MichielsJan Van ElslandePieter VermeerschGlynis FransKristl G ClaeysStefanie DesmetPaul De MunterXavier Bossuyt

Published in: The journal of applied laboratory medicine (2024)

Anti-IFN-α2 autoantibodies were detected in viral infections, myasthenia gravis, and rarely in bacterial infections. ELISA and Luminex screening assays do not give similar results. Nonspecific reactivity and functional assays are necessary to validate the screening test result.

Keyphrases

myasthenia gravis
sars cov
immune response
high throughput