Nasal hyperreactivity in allergic rhinitis and chronic rhinosinusitis with polyps: a role for neuronal pathways.
W BackaertB SteelantT WilsZ QianE DilissenA-C JonckheereB BoonenM JorissenR SchrijversD M A BullensK TalaveraP W HellingsL Van Gerven
Published in: Rhinology (2024)
NHR is not an on/off phenomenon but spans a continuous spectrum of reactivity. A neurogenic inflammatory background and increased histamine-levels are risk factors for NHR in AR/CRSwNP.