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Chikungunya virus infection in Aruba: Diagnosis, clinical features and predictors of post-chikungunya chronic polyarthralgia.

Ralph HuitsJaclyn De KortRiemsdijk Van Den BergLuis ChongAchilleas TsoumanisKaat EggermontKoen BartholomeeusenKevin K AriënJan JacobsMarjan Van EsbroeckEmmanuel BottieauLieselotte Cnops
Published in: PloS one (2018)
We identified 269 CHIKV patients after the first outbreak of Asian genotype CHIKV in Aruba in 2014-2015. RT-PCR yielded 59 (28%) additional CHIKV diagnoses compared to IgM antibody detection alone. Arthralgia, fever and skin rash were the dominant acute phase symptoms. pCHIK-CPA longer than 1 year affected 26% of cases and was predicted by female gender, high ACR-score and CHIKV-RNA detection beyond 7 days of symptom onset.
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