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Hidden myelodysplastic syndrome (MDS): A prospective study to confirm or exclude MDS in patients with anemia of uncertain etiology.

José María BastidaOriana López-GodinoAna Vicente-SánchezSantiago Bonanad-BoixBlanca Xicoy-CiriciJesus M Hernández-SánchezEsperanza SuchJose CerveraJuan C Caballero-BerrocalFélix López-CadenasMario Arnao-HerráizInés RodríguezInmaculada Llopis-CalatayudMaría J JiménezMaria Consuelo Del Cañizo-RoldánMaria Diez Campelo
Published in: International journal of laboratory hematology (2018)
Our prospective, four-step approach is an efficient and logical strategy to facilitate the diagnosis of MDS on the basis of unexplained anemia and/or macrocytosis, and may allow the early diagnosis of the most serious causes of anemia. Molecular analysis of genes related to MDS could be a promising diagnostic and prognostic approach.
Keyphrases
  • iron deficiency
  • chronic kidney disease
  • transcription factor
  • bioinformatics analysis
  • genome wide identification