A molecular sensitization map of European children reveals exposome- and climate-dependent sensitization profiles.

M B Gea KiewietChristian LupinekSusanne VrtalaSandra WieserAlexandra BaarRenata KissInger KullEric MelénMagnus WickmanDaniela PortaDavide GoriUlrike Gehring Rob C AalberseJordi SunyerMarie Standl Joachim HeinrichDagmar WaiblingerJohn WrightJosep M AntóJean Bousquet Marianne van Hage Rudolph Valenta

Published in: Allergy (2023)

We show regional, exposome and climate-dependent differences in molecular IgE-reactivity profiles in Northern, Western/Central and Southern Europe which may form a molecular basis for precision medicine-based approaches for treatment and prevention of allergy.

Keyphrases

climate change
young adults
single molecule
combination therapy
allergic rhinitis