Associations between Ileal Juice Bile Acids and Colorectal Advanced Adenoma.
Hung Nguyen LuuChi Thi-Du TranRenwei WangMai Vu-Tuyet NguyenMo Thi TranThuy Thi-Van TuongQuang Hong TranLinh Cu LeHuong Thi-Thu PhamHien Huy VuNam Chi BuiHien Thi-Thu HaDung Tuan TrinhClaire E ThomasJennifer Adams-HaduchLiudmilla VelikokhatnayaRobert E SchoenGuoxiang XieWei JiaPaolo BoffettaJose C ClementeWoon-Puay KohPublished in: Nutrients (2023)
Colorectal advanced adenoma was associated with altered bile acids in ileal juice. The HCA species may promote the development of colorectal advanced adenoma, whereas gut microbiota responsible for the conversion of CDCA to UDCA may protect against it. Our findings have important implications for the use of bile acids as biomarkers in early detection of colorectal cancer.
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