Quantitative prediction of CYP3A-mediated drug-drug interactions by correctly estimating fraction metabolized using human liver chimeric mice.

Taiji MiyakeTatsuki MochizukiToshito NakagawaMikiko NakamuraChie EmotoNatsuko KomiyamaManabu HirabayashiSatoshi TsurutaTomofumi ShimojoKimio TeraoTatsuhiko Tachibana

Published in: British journal of pharmacology (2023)

Keyphrases

cell therapy
high fat diet induced
high resolution
stem cells
drug induced
mesenchymal stem cells
insulin resistance
mass spectrometry
skeletal muscle