Inline perfusion mapping provides insights into the disease mechanism in hypertrophic cardiomyopathy.
Claudia CamaioniKristopher D KnottJoao B AugustoAndreas SeraphimStefania RosminiFabrizio RicciRedha BoubertakhHui XueRebecca HughesGaby CapturLuis Rocha LopesLouise Anne Elizabeth BrownCharlotte ManistySteffen Erhard PetersenSven PleinPeter KellmanSaidi A MohiddinJames C MoonPublished in: Heart (British Cardiac Society) (2019)
Microvascular dysfunction is common in HCM and associated with hypertrophy and LGE. Perfusion can fall during vasodilator stress and is abnormal even in apparently normal myocardium suggesting it may be an early disease marker.