Involvement of the OTUB1-YAP1 axis in driving malignant behaviors of head and neck squamous cell carcinoma.
Shengjian JinTakaaki TsunematsuTaigo HoriguchiYasuhiro MouriWenhua ShaoKeiko MiyoshiHiroko HagitaMotoharu SaruboNatsumi FujiwaraGuangying QiNaozumi IshimaruYasusei KudoPublished in: Cancer medicine (2023)
This study highlights the critical role of OTUB1 in HNSCC progression via modulating YAP1. Targeting the OTUB1-YAP1 axis holds promise as a potential therapeutic strategy for HNSCC treatment.