Comprehensive analysis of MYB/MYBL1-altered pediatric-type diffuse low-grade glioma.

Daniel C MoreiraIbrahim QaddoumiSusan SpillerThomas W BouldinAlan DavidsonNasjla Saba-SilvaDaniel V SullivanRyuma TanakaAaron S WagnerMatthew WoodPaul KlimoGodwin JobMeenakshi DevidasXiaoyu LiAmar GajjarGiles W RobinsonJason Chiang

Published in: Neuro-oncology (2024)

pLGG with MYB/MYBL1 alterations have good outcomes. Our findings suggest that surgical resectability is a crucial determinant of EFS. Further characterization is required to identify optimal treatment strategies for progressive tumors.

Keyphrases

low grade
transcription factor
high grade
multiple sclerosis
metabolic syndrome
insulin resistance
young adults