Design, Development, In Vitro and Preliminary In Vivo Evaluation of a Novel Photo-Angioplasty Device: Lumi-Solve.
HongBin LiuGopal R SamaAndrea RobinsonSimon MountfordPhilip E ThompsonAndrew RoddaJohn ForsythePatrick J MornanePaul PasicHelmut ThissenMelissa ByrneDavid M KayeAnthony E DearPublished in: Cardiovascular engineering and technology (2021)
Lumi-Solve, a novel DEBc device developed utilizing a combination of chemical, fibre-optic and catheter based technology platforms, demonstrated potential for targeted delivery of bioactive HDACi to the blood vessel wall supporting direct application to the management of NIH and warranting additional in vivo studies.