Serum HBV pregenomic RNA is correlated with Th1/Th2 immunity in treatment-naïve chronic hepatitis B patients.

Yu-Rong GuLubiao ChenYifan LianLin GuYaqiong ChenYanhua BiZexuan HuangYanlin HuangBo HuYuehua Huang

Published in: Journal of medical virology (2019)

Our study confirmed the relationship between serum HBV pgRNA and host immunity. The results demonstrated that serum HBV pgRNA is positively correlated with Th2 immunity but negatively correlated with Th1 immunity, indicating that it might have a relationship with HBV antigen conversion and CTL immunodeficiency in CHB patients.

Keyphrases

hepatitis b virus
end stage renal disease
newly diagnosed
chronic kidney disease
liver failure
prognostic factors
replacement therapy