π-Extended Donor-Acceptor Porphyrins and Metalloporphyrins for Antimicrobial Photodynamic Inactivation.
Anzhela GalstyanYogesh Kumar MauryaHalina ZhylitskayaYoun Jue BaeYi-Lin WuMichael R WasielewskiTadeusz LisUlrich DobrindtMarcin StępieńPublished in: Chemistry (Weinheim an der Bergstrasse, Germany) (2020)
Free base, zinc and palladium π-extended porphyrins containing fused naphthalenediamide units were employed as photosensitizers in antimicrobial photodynamic therapy (aPDT). Their efficacy, assessed by photophysical and in vitro photobiological studies on Gram-positive bacteria, was found to depend on metal coordination, showing a dramatic enhancement of photosensitizing activity for the palladium complex.