Janus mesoporous organosilica/platinum nanomotors for active treatment of suppurative otitis media.
Zhizhou LuoRuonan WangXiaoxia DengTianxiang ChenXuehua MaYujie ZhangChangyong GaoAiguo WuPublished in: Nanoscale (2024)
We report a Janus mesoporous organosilica/platinum (MOS/Pt) nanomotor for active targeted treatment of suppurative otitis media, as a new type of multi-functional ear drop. The efficient propulsion of MOS/Pt nanomotors in hydrogen peroxide ear-cleaning drops significantly improves their binding efficiency with Staphylococcus aureus and enhances their antibacterial efficacy.