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Janus mesoporous organosilica/platinum nanomotors for active treatment of suppurative otitis media.

Zhizhou LuoRuonan WangXiaoxia DengTianxiang ChenXuehua MaYujie ZhangChangyong GaoAiguo Wu
Published in: Nanoscale (2024)
We report a Janus mesoporous organosilica/platinum (MOS/Pt) nanomotor for active targeted treatment of suppurative otitis media, as a new type of multi-functional ear drop. The efficient propulsion of MOS/Pt nanomotors in hydrogen peroxide ear-cleaning drops significantly improves their binding efficiency with Staphylococcus aureus and enhances their antibacterial efficacy.
Keyphrases
  • hydrogen peroxide
  • staphylococcus aureus
  • quantum dots
  • room temperature
  • combination therapy
  • pseudomonas aeruginosa
  • cystic fibrosis
  • reduced graphene oxide
  • smoking cessation
  • metal organic framework
  • ionic liquid