Mouse double minute 2 amplification in oesophageal squamous cell carcinoma is associated with better outcome.
Dongxian JiangLingli ChenJie HuangHao WangQi SongPeng ShiHaixing WangYing-Yong HouPublished in: Histopathology (2020)
MDM2 amplification was significantly correlated with an improved patient outcome, especially in stage I and II disease, and was verified as an independent prognostic factor in our patients. Therefore, MDM2 amplification may be a potential biomarker for risk stratification of the lower stages of ESCC.