Concatemer Assisted Stoichiometry Analysis (CASA): targeted mass spectrometry for protein quantification.

Jiaxi Cai Quan YunCindy Yuxuan ZhangZiyi WangStephen P Hinshaw Huilin Zhou Raymond T Suhandynata

Published in: bioRxiv : the preprint server for biology (2024)

This study presents Concatemer-Assisted Stoichiometry Analysis (CASA) to address a common challenge in cell biological research: quantifying the number of each protein subunit in a native protein complex.

Keyphrases

mass spectrometry
protein protein
amino acid
single cell
binding protein
liquid chromatography
cell therapy
protein kinase
gas chromatography
tandem mass spectrometry
capillary electrophoresis