Association of the combination of weight gain after 20 years of age and current obesity with chronic kidney disease in Japan: a cross-sectional study.

Hirotaka OchiaiTakako ShirasawaTakahiko YoshimotoSatsue NagahamaMariko KobayashiAkira MinouraKeiichiro IkedaEri OzakiHiromi HoshinoAkatsuki Kokaze

Published in: BMJ open (2019)

Weight gain ≥10 kg after 20 years of age was significantly associated with CKD in both obese and non-obese subjects. Moreover, the influence of weight gain ≥10 kg plus obesity on CKD was greater than that of weight gain ≥10 kg plus non-obesity on CKD. The present study results suggest that it is important to consider weight gain after maturity in both obese and non-obese subjects to prevent CKD among Japanese middle-aged adults.

Keyphrases

weight gain
chronic kidney disease
weight loss
end stage renal disease
birth weight
body mass index
bariatric surgery
metabolic syndrome
adipose tissue
obese patients
type diabetes
middle aged
insulin resistance
physical activity
preterm birth
high fat diet induced