Dopamine agonist serum concentrations and impulse control disorders in Parkinson's disease.

Sara C StauboOle Martin FuskevågMathias ToftIngeborg H LieKirsti M J AlvikPål JostadStein H TingvollHallvard LillengKristina RosqvistElisabet StørsetPer OdinEspen DietrichsErik Sveberg Dietrichs

Published in: European journal of neurology (2023)

The use of pramipexole may in itself confer high ICD risk, whereas ICDs among ropinirole users depend more on serum concentration and drug exposure. The pharmacokinetic properties of ropinirole make it challenging to predict its effects on patients, which supports the need for therapeutic drug monitoring to reduce risk of ICD.

Keyphrases

end stage renal disease
ejection fraction
chronic kidney disease
newly diagnosed
prognostic factors
emergency department
patient reported outcomes