Prevalence of problematic pharmaceutical opioid use in patients with chronic non-cancer pain: A systematic review and meta-analysis.
Kyla H ThomasMichael N DaliliHung-Yuan ChengSarah DawsonNick DonnellyJulian P T HigginsMatthew HickmanPublished in: Addiction (Abingdon, England) (2024)
Problematic pharmaceutical opioid use appears to be common in chronic pain patients treated with opioid analgesics, with nearly one in 10 experiencing dependence and opioid use disorder, one in three showing signs and symptoms of dependence and opioid use disorder and one in five showing aberrant behaviour.