Dopamine D1- and D2-like receptors oppositely regulate lifespan via a dietary restriction mechanism in Caenorhabditis elegans.

Yizhou JiangUma GaurZhibai CaoSheng-Tao HouWenhua Zheng

Published in: BMC biology (2022)

These data demonstrated a novel role of dopamine receptors in lifespan and dietary restriction regulation. The clinically approved antipsychotic aripiprazole holds potential as a novel anti-aging drug.

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