Genotypic and phenotypic characterization of influenza A viral variants in study participants treated with pimodivir in the phase 2b TOPAZ study.

Johan VingerhoetsIlse Van DrommeWilbert van DuijnhovenDavid AndersonSandra De MeyerLorant Leopold

Published in: Antiviral therapy (2023)

Participants with acute uncomplicated influenza A treated with pimodivir in the TOPAZ study infrequently developed reduced susceptibility to pimodivir and combining pimodivir with oseltamivir further decreased the risk of reduced susceptibility development.

Keyphrases

gene expression
intensive care unit
hepatitis b virus
liver failure
extracorporeal membrane oxygenation
copy number
urinary tract infection
newly diagnosed