Protective Effects of Six Selected Dietary Compounds against Leptin-Induced Proliferation of Oestrogen Receptor Positive (MCF-7) Breast Cancer Cells.

Meran Keshawa EdiriweeraKamani Hemamala TennekoonSameera Ranganath SamarakoonIra ThabrewE Dilip de Silva

Published in: Medicines (Basel, Switzerland) (2017)

Considering the high prevalence of obesity, this observation provides a rationale for use of curcumin, quercetin and EGCG as antagonists of leptin in the treatment of obese breast cancer patients.

Keyphrases

breast cancer cells
weight loss
metabolic syndrome
type diabetes
insulin resistance
adipose tissue
diabetic rats
high glucose
clinical trial
signaling pathway
bariatric surgery
oxidative stress
weight gain
body mass index
obese patients
replacement therapy