Tranexamic acid does not affect intraoperative blood loss or in-hospital outcomes after acetabular fracture surgery.
Harsh WadhwaSeth S TigchelaarMichael J ChenJayme C B KoltsovMichael J BellinoJulius A BishopMichael J GardnerPublished in: European journal of orthopaedic surgery & traumatology : orthopedie traumatologie (2021)
In this study, perioperative IV TXA did not decrease blood loss, need for transfusion, or improve in-hospital outcomes of acetabular fracture surgery. Age 60-70, CCI, ISS, and fracture patterns likely to bleed were independently associated with intraoperative transfusion. Anterior surgical approach and need for intraoperative transfusion were independently associated with postoperative transfusion. Further prospective trials are warranted to confirm these findings.
Keyphrases
- cardiac surgery
- patients undergoing
- minimally invasive
- sickle cell disease
- coronary artery bypass
- acute kidney injury
- healthcare
- hip fracture
- total hip
- total hip arthroplasty
- surgical site infection
- neuropathic pain
- adverse drug
- type diabetes
- spinal cord injury
- metabolic syndrome
- adipose tissue
- total knee arthroplasty
- weight loss
- acute coronary syndrome
- atrial fibrillation
- glycemic control