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Early detection of dopaminergic dysfunction and glymphatic system impairment in Parkinson's disease.

Jun YaoTing HuangYouyong TianHongdong ZhaoRushuai LiXindao YinSong'an ShangYu-Chen Chen
Published in: Parkinsonism & related disorders (2024)
DTI-ALPS has the potential to uncover glymphatic dysfunction in patients with PD, with this dysfunction correlating strongly with the severity of disease, together with the mean putaminal and caudal SUVR. PET- MRI can serve as a potential multimodal imaging biomarker for early-stage PD.
Keyphrases
  • early stage
  • oxidative stress
  • magnetic resonance imaging
  • high resolution
  • computed tomography
  • human health
  • contrast enhanced
  • squamous cell carcinoma
  • pain management
  • radiation therapy
  • white matter
  • lymph node