A Sex-Specific Role of Endothelial Sirtuin 3 on Blood Pressure and Diastolic Dysfunction in Female Mice.

Published in: International journal of molecular sciences (2020)

These results implicate a sex-specific role of endothelial SIRT3 in regulating blood pressure and diastolic function in mice. Deficiency of endothelial SIRT3 may be responsible for a diastolic dysfunction in aged female.

Keyphrases

blood pressure
oxidative stress
hypertensive patients
endothelial cells
left ventricular
heart rate
high fat diet induced
ejection fraction
blood glucose
type diabetes
metabolic syndrome
skeletal muscle
weight loss
smoking cessation