Identification of the Key Genes Involved in the Tumorigenesis and Prognosis of Prostate Cancer.

Wenxuan Wang Qinghui Wu Ali Mohyeddin Yousheng Liu Zhitao Liu Jianqiang Ge Bao Zhang Gan Shi Weifu Wang Dinglan Wu Fei Wang

Published in: Computational and mathematical methods in medicine (2022)

TOP2A, NCAPG, and BUB1B are important genes intimately linked to the clinical prognosis of PCa and can be employed as reliable biomarkers for early diagnosis and prognosis. Moreover, these genes can provide a theoretical basis for precision differentiation and treatment of PCa.

Keyphrases

prostate cancer
bioinformatics analysis
genome wide
genome wide identification
dna methylation
transcription factor
replacement therapy