Twins' risk of childhood asthma mediated by gestational age and birthweight.

Vilhelmina UllemarC LundholmC Almqvist

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2016)

Twins were at significantly higher unadjusted risk of asthma or early life wheeze compared to singletons in the younger, but not in the older cohort. Associations attenuated following adjustment for GA/BW, suggesting that GA/BW mediates the effect of twinship on asthma risk. After adjustments, twins were at lower risk of asthma outcomes, possibly due to unmeasured confounding.

Keyphrases

gestational age
chronic obstructive pulmonary disease
early life
lung function
birth weight
preterm birth
allergic rhinitis
pet ct
physical activity
cystic fibrosis
air pollution
metabolic syndrome
weight loss